Scientific Articles
Scientific studies relating to regenerative medicine and ACell specifically.
Tissue-Engineered Myocardial Patch Derived From Extracellular Matrix Provides Regional Mechanical Function
Brief: Using a canine model, a full thickness defect in the right ventricle was repaired with either Dacron or ECM. A third group had no surgery and determined baseline RV function. (Adobe PDF File)
Esophageal Reconstruction with ECM and Muscle Tissue in a Dog Model
Brief: An in vivo study was conducted to determine if an extracellular matrix (ECM) scaffold co-localized with autologous muscle tissue could achieve constructive remodeling of esophageal tissue without stricture. (Adobe PDF File)
Evaluation of the safety and efficacy of the ACell Vet UBM powder as a treatment for musculotendinous and/or ligamentous repair in equine patients
Brief: All horses treated with the ACell Vet powder showed increased linear fiber pattern formation beginning at 28 -56 days. The horses treated with just conventional therapies did not show this constructive remodeling. (Adobe PDF File)
Sphincter Augmentation for Urinary Incontinence in Dogs
Brief: Urinary incontinence can be either an acquired or congenital condition most commonly found in larger breed dogs. The condition is often associated with oophorectomy. Medical treatments for this condition are reasonably effective and usually consist of phenylpropanolamine administered daily and/or estrogen therapy. (Adobe PDF File)
Extracellular Matrix Scaffold for Cardiac Repair
Brief: Chronic congestive heart failure plagues an increasing population of cardiac patients worldwide. ACellular xenogeneic extracellular matrix has been used successfully as a constructive scaffold for the repair and replacement of numerous tissues and organs in both preclinical studies and human clinical applications. (Adobe PDF File)
